"Pathomolecular Mechanisms - Understanding the origins of diseases"
Immunregulation of inflammatory mediators after low dose allergen provocation and/or LPS inhalation challenge
Inflammation, allergy and autoimmune diseases: exploring the impact of nitric oxide on wound healing, the central role of the extracellular matrix in tissue remodelling and the function of phospholipase A2 subtypes in the skin of healthy individuals and of patients with allergic or autoimmune diseases
Design of tumor-specific treatment modalities in human virus-associated malignancies (EBV, HPV) and investigation of pro-apoptotic activation mechanisms in human cancer (colon, Burkitt lymphoma, lung)
Detailed assessment and monitoring of immunological parameters in human patients, especially in Nephritis, Kidney Transplantation, Rheumatoid Arthritis, Inflammatory Bowel Disease, Autoimmune Endocrinopathy and Lymphatic Leukemia after Stem Cell Transplantation Anxiety, Depression , Dementia & Aging: Apoptosis & Neuroinflammation Screening of patient materials (from blood to articular tissues) for pathologic changes at a molecular dimension in rheumatic diseases Regulation of the cellular eicosanoid-synthesis by pathophysiological stimuli involved in inflammatory diseases Chromosomal translocations of the human MLL gene and functional characterization of MLL fusion proteins Analyzing oncogenic switches in high-risk acute lymphoblastic leukemia
Role of epoxyeicosatrienoic acids (EETs) in vascular function and inflammation
