Institute for pharmaceutical technology -
Director Prof. Dr. Jennifer Dressman

 

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Expertise

  • Prediction of the oral absorption of drugs
  • Improvement of oral absorption through formulation
  • Better therapy of inflammatory diseases of the gastrointestinal tract

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Resources and Abilities

  • Production of solid dosage forms, including pellet, tablet and coating technologies, under Good Manufacturing Practice requirements
  • Dissolution testing, including development of biorelevant tests (with a view to in vitro-in vivo correlation)
  • Analytical capabilities for in vitro and biological samples
  • Software for establishing in vitro-in vivo correlations

 

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Publications

  • M.W. Rudolph, S.Klein, T.E. Beckert, H-U. Petereit, J.B. Dressman A new 5-aminosalicylic acid multi-unit dosage form for the therapy of ulcerative colitis
    Eur. J. Pharm. Biopharm. 51:183-190 (2001)

  • E. Nicolaides, M. Symillides, J.B. Dressman, C. Reppas Biorelevant dissolution testing to predict the plasma profile of highly lipophilic drugs after oral administration. Pharm Res 18 (3):380-388 (2001)

  • E. Kostewicz, U. Brauns, R. Becker, J.B. Dressman Forecasting the oral absorption behaviour of poorly soluble weak bases using solubility and dissolution studies in biorelevant media Pharm Research, 19 (3): 345-349 (2002)

  • A. Scholz, B. Abrahamsson, S. Diebold, E. Kostewicz, B. Polentarutti, A-L. Ungell, J.B.Dressman Influence of hydrodynamics and particle size on the oral absorption of felodipine in Labradors. Pharm Res 19 (1):42-46 (2002)

  • S. Willmann, W. Schmitt, J. Keldernich, JB Dressman A Physiological Model for Simulating Gastrointestinal Flow and Drug Absorption in the Rat.
    Pharm Res 20 (11):1766 (2003)

 

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Staff:

  • Sandra Klein, Apothekerin
  • Marc Lindenberg, Apotheker
  • Thomas Fürst. Apotheker
  • Martin Wunderlich, Apotheker
  • Matthias Fischbach, Apotheker

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ZAFES-Coordinator:

 

 

 

INSTITUTES AND
MEDICAL CENTERS

 
 

RHEUMATOLOGY

 
 

GASTROENTEROLOGY - HEPATOLOGY

 
 

PAEDIATRIC HAEMATOL., ONCOL. & HAEMOSTASEOLOGY

 
 

NEURORADIOLOGY

 
 

CLINICAL PHARMACOLOGY

 
 

GENERAL PHARMACOLOGY &
TOXICOLOGY

 
 

IMMUNE PHARMACOLOGY

 
 

INTERDISCIPLINARY PHARMACOLOGY

 

PHARMACEUTICAL TECHNOLOGY

 

PROF. DRESSMAN
PROF. KREUTER

 
 
 

PHARMACEUTICAL CHEMISTRY

 
 

PHARMACEUTICAL
BIOLOGY

 
 

GEORG SPEYER HAUS

 
 

FOOD CHEMISTRY

 
 

ORGANIC CHEMISTRY &
CHEMICAL BIOLOGY

 
 

NEUROLOGY

 
 

ANESTHESIOLOGY, INTENSIVE CARE AND
PAIN CONTROL

 
 

OBSTETRICS AND GYNECOLOGY

 
 

DEPARTMENT OF DERMATOLOGY & VENEROLOGY

 
 

CARDIOVASCULAR PHYSIOLOGY

 
 

PEDIATRIC PNEUMOLOGY, ALLERGY AND CYSTIC FIBROSIS

MEDICAL VIROLOGY

ECOLOGY, EVOLUTION AND DIVERSITY, DEPARTMENT AQUATIC ECOTOXICOLOGY

 
 

ORAL, CRANIO-
MAXILLOFACIAL AND
FACIAL PLASTIC SURGERY

 
 

GENERAL AND VASCULAR SURGERY

 
 

CLINICAL NEUROANATOMY

 
 

GENERAL PEDIATRICS

 
 

HAEMATOLOGY, ONCOLOGY

 
 

DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY

 
 

BIOCHEMISTRY

 
 

GENERAL PRACTICE

 
 

MPI FOR
BRAIN RESEARCH