Institute for pharmaceutical
technology -
Director Prof. Dr. Jennifer
Dressman
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Expertise
- Prediction of the oral
absorption of drugs
- Improvement of oral absorption
through formulation
- Better therapy of inflammatory
diseases of the gastrointestinal
tract
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Resources
and Abilities
- Production of solid dosage
forms, including pellet, tablet
and coating technologies,
under Good Manufacturing Practice
requirements
- Dissolution testing, including
development of biorelevant
tests (with a view to in vitro-in
vivo correlation)
- Analytical capabilities
for in vitro and biological
samples
- Software for establishing
in vitro-in vivo correlations
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Publications
- M.W. Rudolph, S.Klein, T.E.
Beckert, H-U. Petereit, J.B.
Dressman A new 5-aminosalicylic
acid multi-unit dosage form
for the therapy of ulcerative
colitis
Eur. J. Pharm. Biopharm. 51:183-190
(2001)
- E. Nicolaides, M. Symillides,
J.B. Dressman, C. Reppas Biorelevant
dissolution testing to predict
the plasma profile of highly
lipophilic drugs after oral
administration. Pharm Res
18 (3):380-388 (2001)
- E. Kostewicz, U. Brauns,
R. Becker, J.B. Dressman Forecasting
the oral absorption behaviour
of poorly soluble weak bases
using solubility and dissolution
studies in biorelevant media
Pharm Research, 19 (3): 345-349
(2002)
- A. Scholz, B. Abrahamsson,
S. Diebold, E. Kostewicz,
B. Polentarutti, A-L. Ungell,
J.B.Dressman Influence of
hydrodynamics and particle
size on the oral absorption
of felodipine in Labradors.
Pharm Res 19 (1):42-46 (2002)
- S. Willmann, W. Schmitt,
J. Keldernich, JB Dressman
A Physiological Model for
Simulating Gastrointestinal
Flow and Drug Absorption in
the Rat.
Pharm Res 20 (11):1766 (2003)
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Staff:
- Sandra Klein, Apothekerin
- Marc Lindenberg, Apotheker
- Thomas Fürst. Apotheker
- Martin Wunderlich, Apotheker
- Matthias Fischbach, Apotheker
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ZAFES-Coordinator:
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