Department for Neurology -
Prof. Dr. med. M. Sitzer

Expertise

atherosclerosis (mechanisms of destabilization, progression, HIV as a risk factor, long term prognosis of intra- and extracranial stent implantation)
stroke (role of molecular markers, prevention of post stroke depression)
cerebral small vessel disease (autoregulation studies, effects of statins, stroke scales)
Neurosonologic diagnostic (characterization of the vertebral system, echogenicity of the substantia nigra)
Planning and supervision of multicenter clinical trials (PREDIS)

Resources and Abilities

Ultrasound laboratory (ECD, TCD, Duplex, TCCD)
functional ultrasound diagnostics (microemboli detection, Echovist-TCD, multimodal autoregulation measurements)

Publikations

Lorenz MW, von Kegler S, Steinmetz H, Markus HS, Sitzer M. Carotid intima-media thickening indicates a higher vascular risk across a wide age range: prospective data from the Carotid Atherosclerosis Progression Study (CAPS). Stroke. 2006 Jan;37(1):87-92
Kahles T, Foerch C, Sitzer M, Schroeter M, Steinmetz H, Rami A, Neumann-Haefelin T. Tissue plasminogen activator mediated blood-brain barrier damage in transient focal cerebral ischemia in rats: relevance of interactions between thrombotic material and thrombolytic agent. Vascul Pharmacol. 2005 Oct;43(4):254-9
Foerch C, Curdt I, Yan B, Dvorak F, Hermans M, Berkefeld J, Raabe A, Neumann-Haefelin T, Steinmetz H, Sitzer M. Serum glial fibrillary acidic protein as a biomarker for intracerebral haemorrhage in patients with acute stroke. J Neurol Neurosurg Psychiatry. 2006 Feb;77(2):181-4
Foerch C, Misselwitz B, Sitzer M, Berger K, Steinmetz H, Neumann-Haefelin T; Arbeitsgruppe Schlaganfall Hessen. Difference in recognition of right and left hemispheric stroke. Lancet. 2005 Jul 30-Aug 5;366(9483):392-3.
Foerch C, Singer OC, Neumann-Haefelin T, du Mesnil de Rochemont R, Steinmetz H, Sitzer M. Evaluation of serum S100B as a surrogate marker for long-term outcome and infarct volume in acute middle cerebral artery infarction. Arch Neurol. 2005 Jul;62(7):1130-4.
Trostdorf F, Buchkremer M, Harmjanz A, Kablau M, Jander S, Geiger K, Schmitz-Rixen T, Steinmetz H, Sitzer M. Fibrous cap thickness and smooth muscle cell apoptosis in high-grade carotid artery stenosis. Eur J Vasc Endovasc Surg. 2005 May;29(5):528-35.
Bevan S, Porteous L, Sitzer M, Markus HS. Phosphodiesterase 4D gene, ischemic stroke, and asymptomatic carotid atherosclerosis. Stroke. 2005 May;36(5):949-53
Jerrard-Dunne P, Sitzer M, Risley P, Buehler A, von Kegler S, Markus HS. Inflammatory gene load is associated with enhanced inflammation and early carotid atherosclerosis in smokers. Stroke. 2004 Nov;35(11):2438-43