Institute for food chemistry-
Prof. Dr. rer. nat. Armin Mosandl

Expertise

Authenticity of natural componds
AG Prof. Dr. A. Mosandl
Basic research in biogenesis of natural compounds.
AG Prof. Dr. A. Mosandl
Stable isotope analysis
AG Prof. Dr. A. Mosandl
Chiral stationary phases
AG Prof. Dr. A. Mosandl
Therapy accompanying analysis of inherited metabolic deseases
AG Prof. Dr. A. Mosandl

Resources and Abilities

Mass spectrometry (GC/GC/MS) 3 configurations
Mass spectrometry (GC/GC/MS/MS)
Isotope ratio - Mass spectrometry [GC-combustion-IRMS (d13C)]
Isotope ratio - Mass spectrometry [GC-combustion / reduction-IRMS (d15N)]
Isotope ratio - Mass spectrometry [GC-pyrolysis-IRMS (d18O, d2H)]
Isotope ratio - Mass spectrometry [Thermochemical conversion/Element Analyzer-IRMS (d18O, d2H)]

Publications

Mosandl A. Enantioselective capillary gas chromatography and stable isotope ratio mass spectrometry in the authenticity control of flavors and essential oils. Food Reviews Int 1995;11:597-664
(AUTHENTICITY OF NATURAL COMPOUNDS)
Juchelka D, Beck T, Hener U, Dettmar F, and Mosandl A. Multidimensional gas chromatography, online coupled with isotope ratio mass spectrometry (MDGC-IRMS): Progress in the analytical authentication of genuine flavor components. J High Resolut Chromatogr 1998;21:145-151
(STABLE ISOTOPE ANALYSIS)
Wüst M, and Mosandl A. Wein ist ein besonderer Saft - Zur Biosynthese von Duft- und Aromastoffen höherer Pflanzen. Forschung Frankfurt 2002;3:8–15
(BIOGENESIS OF NATURAL COMPOUNDS)
Dietrich A, Maas B, Karl V, Kreis P, Lehmann D, Weber B, and Mosandl A. Stereoisomeric Flavor Compounds, Part LV: Stereodifferentiation of some chiral volatiles on heptakis (2,3-di-O-acetyl-6-O-tert-butyl-dimethylsilyl)-b-cyclodextrin. J High Resolut Chromatogr 1992;15:176-179.
(CHIRAL STATIONARY PHASES)
Dietrich A, Maas B, Messer W, Bruche G, Karl V, Kaunzinger A, and Mosandl A. Stereoisomeric Flavor Compounds Part: LVIII: The use of heptakis (2,3-di-O-methyl-6-O-tert.-butyldimethylsilyl)-b-cyclodextrin as a chiral stationary phase in flavor analysis. J High Resolut Chromatogr 1992;15:590-593
(CHIRAL STATIONARY PHASES)
Kaunzinger A, Rechner A, Beck T, Mosandl A, Sewell AC, and Böhles H. Chiral compounds as indicators of inherited metabolic disease. Simultaneous stereodifferentiation of lactic-, 2-hydroxyglutaric- and glyceric acid by enantioselective cGC. Enantiomer 1996;1:177-182.
(THERAPY ACCOMPANYING ANALYSIS)
Podebrad F, Heil M, Leib S, Geier B, Beck T, Mosandl A, Sewell AC, and Böhles H. Analytical approach in diagnosis of inherited metabolic diseases: Maple syrup disease (MSUD) - Simultaneous analysis of metabolites in urine by enantioselective multi-dimensional capillary gas chromatography - mass spectrometry (enantio-MDGC-MS). J High Resolut Chromatogr 1997;20:355-362.
(THERAPY ACCOMPANYING ANALYSIS)
Heil M, Podebrad F, Beck T, Mosandl A, Sewell AC, and Böhles H. Enantioselective multidimensional gas chromatography - mass spectrometry (enantio-MDGC-MS) in analysis of urinary organic acids. J Chromatogr B 1998;714:119-126.
(THERAPY ACCOMPANYING ANALYSIS)
Podebrad F, Heil M, Reichert S, Mosandl A, Sewell AC, and Böhles H. 4,5-Dimethyl-3-hydroxy-2[5H]-furanone (sotolone) - the odour of maple syrup urine disease. J Inher Metab Dis 1999;22:107-114.
(THERAPY ACCOMPANYING ANALYSIS)
Sewell AC, Mosandl A, and Böhles H. False Diagnosis of Maple Syrup Urine Disease Owing to Ingestion of Herbal Tea. New England J Med 1999;341:769 – 770.
(THERAPY ACCOMPANYING ANALYSIS)
Podebrad F, Heil M, Scharrer A, Feldmer S, Schulte-Mäter O, Mosandl A, Sewell AC, and Böhles H. Analysis of methylcitric acid by enantioselective multidimensional gas chromatography-mass spectrometry. J High Resol Chromatogr 1999;22:604 – 608.
(THERAPY ACCOMPANYING ANALYSIS)
Podebrad F, Heil M, Beck T, Mosandl A, Sewell AC, and Böhles H. Stereodifferentiation of 3-Hydroxyisobutyric- and 3-Aminoiso-butyric Acid in Human Urine by Enantioselective Multidimensional Capillary Gas Chromatography-Mass Spectrometry. Clin Chim Acta 2000;292:93 –105
(THERAPY ACCOMPANYING ANALYSIS)
Heil M, Podebrad F, Prado E, Beck T, Mosandl A, Sewell AC, Böhles H, and Lehnert W. Enantioselective analysis of ketone bodies in patients with b-ketothiolase deficiency, medium-chain acyl coenzyme A dehydrogenase deficiency and ketonemic vomiting. J. Chromatogr B 2000;739:313-324.
(THERAPY ACCOMPANYING ANALYSIS)
Sewell AC, Heil M, Mosandl A, and Böhles H. Rapid enantiomeric differentiation of urinary metabolites in a patient with bacterial overgrow syndrome. Clin Chem 2000:46:1444 - 1445.
(THERAPY ACCOMPANYING ANALYSIS)