Institute for Oral, Cranio-Maxillofacial and Facial Plastic Surgery -
Prof. Dr. Dr. Dr. Robert Sader

>

Expertise

Besides expanding its medical care and teaching, the department is working to establish an efficient research infrastructure as its third column. The existing spectrum of research, based on cancer cell biology, angiogenesis, surgery of malformations and the use of new resorbable materials, has been markedly extended to include focal points of the medical faculty (immunology) and of the university (e-learning).

Another important development is increased cooperation with the nearby technical university of Darmstadt and the university medical center in Mainz for the domain of applied material science and with the European technical college Fresenius in Idstein in the area of cognitive speech science.

>

Resources and Abilities

• Surgery of cleft lip and palate—new operative concepts and techniques that incorporate bio-psychomotor parameters and parameters of speech function
  
• Oncology—molecular biological parameters in multimodal cancer therapy, rehabilitation-oriented treatment concepts
  
• Stem-cell-based angiogenesis—intraoral wound healing, effect of salivary factors
  
• Laser-aided procedures—laser treatment of human hard tissue (bone, cartilage, teeth), photodynamic therapy of periimplantitis, holographic 3D imaging
  
• Applied material science—manufacturing of bioactive surfaces, development of new “intelligent” and resorbable materials, use of novel hybrid implants
  
• Tissue engineering of bone—angiogenesis, interaction on interfaces “biological tissue–man-made material,” rapid prototyping of scaffolds
  
• Head & neck sonography—3D diagnostics, interventional ultrasound, acoustic grid microscopy
  
• Computer-assisted surgery—mathematical modeling and simulation, 3D visualization, virtual and augmented reality for intraoperative navigation
  
• Scientific networking—development and use of new technologies for telemedicine and e-Learning appliance
  
  

>

Staff

• 4 senior physicians
  
• 8 double approbated physicians
  
• 2 dentists

>

Publications

• Stubinger S, Landes C, Seitz O, Zeilhofer HF, Sader R: Ultrasonic bone cutting in oral surgery: a review of 60 cases. Ultraschall Med (2008) 29:66-71.
  
• Schiefelbein D, Seitz O, Goren I, Dibmann JP, Schmidt H, Bachmann M, Sader R, Geisslinger G, Pfeilschifter J, Frank S: Keratinocyte-derived VEGF biosynthesis represents a pleiotropic side effect of PPAR{gamma} agonist troglitazone but not rosiglitazone and involves activation of p38 MAPK: implications for diabetes-impaired skin repair. Mol Pharmacol (2008).
  
• Landes CA, Stubinger S, Laudemann K, Rieger J, Sader R: Bone harvesting at the anterior iliac crest using piezoosteotomy versus conventional open harvesting: a pilot study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2008) 105:e19-28.
  
• Landes CA, Stubinger S, Rieger J, Williger B, Ha TK, Sader R: Critical evaluation of piezoelectric osteotomy in orthognathic surgery: operative technique, blood loss, time requirement, nerve and vessel integrity. J Oral Maxillofac Surg (2008) 66:657-674.
  
• Landes CA, Day K, Glasl B, Ludwig B, Sader R, Kovacs AF: Prospective evaluation of closed treatment of nondisplaced and nondislocated mandibular condyle fractures versus open reposition and rigid fixation of displaced and dislocated fractures in children. J Oral Maxillofac Surg (2008) 66:1184-1193.
  
• Landes CA, Laudemann K, Sader R, Mack M: Prospective changes to condylar position in symphyseal distraction osteogenesis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2008) 106:163-172.
  
• Landes CA, Glasl B, Kopp S, Sader R, Ludwig B: Microanchor mediated upper molar intrusion in deep posterior bite after long-term edentulousness for prosthetic reconstruction with dental implants. Oral Maxillofac Surg (2008) 12:155-158.
  
• Landes CA, Day K, Lipphardt R, Sader R: Prospective closed treatment of nondisplaced and nondislocated condylar neck and head fractures versus open reposition internal fixation of displaced and dislocated fractures. Oral Maxillofac Surg (2008) 12:79-88.
  
• Landes CA, Stubinger S, Ballon A, Sader R: Piezoosteotomy in orthognathic surgery versus conventional saw and chisel osteotomy. Oral Maxillofac Surg (2008) 12:139-147.
  
• Landes CA, Day K, Lipphardt R, Sader R: Closed versus open operative treatment of nondisplaced diacapitular (Class VI) fractures. J Oral Maxillofac Surg (2008) 66:1586-1594.
  
• Bisdas S, Chambron Pinho N, Smolarz A, Sader R, Vogl TJ, Mack MG: Biphosphonate-induced osteonecrosis of the jaws: CT and MRI spectrum of findings in 32 patients. Clin Radiol (2008) 63:71-77.
  
• Ballon A, Landes CA, Zeilhofer HF, Herzog M, Klein C, Sader R: The importance of the primary reconstruction of the traumatized anterior maxillary sinus wall. J Craniofac Surg (2008) 19:505-509.
  
• Stubinger S, Kober C, Zeilhofer HF, Sader R: Er:YAG laser osteotomy based on refined computer-assisted presurgical planning: first clinical experience in oral surgery. Photomed Laser Surg (2007) 25:3-7.
  
• Stubinger S, Landes C, Seitz O, Sader R: Er:YAG laser osteotomy for intraoral bone grafting procedures: a case series with a fiber-optic delivery system. J Periodontol (2007) 78:2389-2394.
  
• Seitz O, Landes C, Dissmann JP, Sader R, Klein C: [First experiences in maxillary arch expansion using the MWD (Maxillary Widening Device)]. Mund Kiefer Gesichtschir (2007) 11:327-332.
  
• Ludwig B, Glasl B, Sader R, Schopf P: [Conservative orthodontic primary care of four newborns with the Pierre-Robin sequence triad]. J Orofac Orthop (2007) 68(1):56-61.
  
• Landes CA, Goral WA, Sader R, Mack MG: Three-dimensional versus two-dimensional sonography of the temporomandibular joint in comparison to MRI. Eur J Radiol (2007) 61:235-244.
  
• Landes CA, Trolle M, Sader R: Rapid 3-dimensional anthropometry by semiautomatic data acquisition and processing. Ann Plast Surg (2007) 58:698-703.
  
• Landes CA, Stuckensen T, Jaquiery C, Sader R: Bone and plate fixation device for transoral osteofixation in the mandibular angle, ramus, and condyle region. J Oral Maxillofac Surg (2007) 65:2115-2118.
  
• Landes CA, Sader R: Sonographic evaluation of the ranges of condylar translation and of temporomandibular joint space as well as first comparison with symptomatic joints. J Craniomaxillofac Surg (2007) 35:374-381.
  
• Kovacs AF, Megahed W, Scholz M, Sader R: [Survival improvement of a unicentric overall population in 20 years: 1038 patients with oral and oropharyngeal squamous cell cancer 1983-2004]. Mund Kiefer Gesichtschir (2007) 11:267-283.
  
• Ballon A, Landes CA, Sader R, Kovacs AF: Interdisciplinary rehabilitation of a patient with Opitz C-syndrome and extensive craniofacial malformation. J Craniofac Surg (2007) 18:287-294.
  
• Landes CA, Goral W, Mack MG, Sader R: 3-D sonography for diagnosis of osteoarthrosis and disk degeneration of the temporomandibular joint, compared with MRI. Ultrasound Med Biol (2006) 32:627-632.
  
• Landes CA, Goral WA, Sader R, Mack MG: 3-D sonography for diagnosis of disk dislocation of the temporomandibular joint compared with MRI. Ultrasound Med Biol (2006) 32:633-639.