General Surgery -
Dr. Christoph W. Strey

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Expertise

• Cell differentiation Analysis and protein synthesis of primary human hepatocytes in culture
  
• Proteom-Analysis of cellular metabolism in human hepatocytes and tumor cell lines
  
• Inflammatory Regulation of Liver regeneration
  
  

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Resources and Abilities

• Flow cytometry, Two-Dimensional-Gel-Electrophoresis
  
• Protein-Analysis
  
• Real-Time-PCR, conventional PCR-systems
  
• Harvest and cell culture of primary human hepatocytes
  
• Cell biology, culturing and expansion
  
• Immunohistochemistry
  
  

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Co-workers and members of the team

• Elsie Oppermann (Lab-supervisor, Biochemistry)
  
• Maria Rosa Marquez-Pinilla (Tumor biology, Multiplex Analysis)
  
• Maria Park (Laser capture microdissection)
  
• Sybille Beierlein (Cell culture, Protein Analysis)
  
• Kay Weipert (Histopathology/Immunohistochemistry)
  
• Lea Schamell (Cell culture, Protein Analysis)
  
  

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Publications

• Moench C, Burck I, Bug R, Bak YJ, Richter B, Schroeder R, Klarner A, Strey CW, Vogl T, Bechstein W. Hepatic Angiomyolipoma – a Rare Liver Tumor. Z Gastroenterol (2008) 46: 54-57.
  
• Wiegratz I, Kissler S, Engels K, Strey C, Kaufmann M. Umbilical endometriosis in pregnancy without previous surgery. Fertil Steril (2007) Sep 28.
  
• Strey CW, Winters M, Markiewski M, Lambris J.D. Partial hepatectomy induced liver proteome changes in mice. Proteomics (2005) 5: 318-325
  
• Strey CW, Spellman D, Stieber A, Gonatas JO, Wang X, Lambris JD, Gonatas NK. Dysregulation of stathmin, a microtubule-destabilizing protein, and up-regulation of hsp25, hsp27, and the antioxidant peroxiredoxin 6 in a mouse model of familial amyotrophic lateral sclerosis. Am.J.Pathol (2004) 165: 1701-1718.
  
• Markiewski MM, Mastellos D, Tudoran R, DeAngelis RA, Strey CW, Franchini S, Wetsel RA, Erdei A, Lambirs JD. C3a and C3b Activation Products of the Third Component of Complement (C3) Are Critical for Normal Liver Recovery after Toxic Injury. J. Immunol (2004) 173: 747-754.
  
• Grotz W, Siebig S, Olschewski M, Strey CW, Peter K. Low-dose aspirin therapy is associated with improved allograft function and prolonged allograft survival after kidney transplantation. Transplantation (2004) 77: 1848-1853.
  
• Strey CW, Markiewski M, Mastellos D, Tudoran R, Greenbaum L, Lambirs JD. The Proinflammatory Mediators C3a and C5a Are Essential for Liver Regeneration. J. Exp. Med (2003) 198: 913-923.
  
• Manz T, Ochs A, Bisse E, Strey C, Grotz W. Liver support – a task for nephrologists? Extracorporeal treatment of a patient with fulminant Wilson crisis. Blood Purif (2003) 21: 232-6.
  
• Riedemann NC, Guo RF, Neff TA, Laudes IJ, Leller KA, Sarma VJ, Markiewski MM, Mastellos D, Strey CW, Pierson CL, Lambirs JD, Zetoune FS, Ward PA. Increased C5a receptor expression in sepsis. Journal of Clinical Investigation (2002) 110: 101-8.