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Based on a vertical approach to mechanistic research, the institute offers a broad spectrum of expertise from the molecular analysis of individual enzymes to integrative physiology. Research aims on the discovery and understanding of mechanisms and pathways controlling vascular homeostasis, development and function. Emphasis is put on aspects of endothelial cell biology, oxidative and nitrosative stress, angiogenesis and lipid signaling, seeking the identification of new therapeutic targets for cardiovascular disease, inflammation and cancer treatment.
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