Clinic of anesthesiology, intensive care and pain control
Study group: Prof. Dr. med. B. Zwißler

Expertise

Large and small animal models under general anesthesia and controlled mechanical ventilation
Clinical therapy studie

Resources and Abilities

Animal models of inhalational application of compounds in ventilated small animals and models of evaluation of inflammatory reaction
Animal models for the inhalational application of compounds in ventilated small animals with complex hemodynamic monitoring
Recruitment of patients for the winning of samples relevant to research and for therapy studies
Laboratory for cell culture
Western blotting
NO realease in cultivated cells
Polymerase-Chain-Reaction

Publications

M. Kleen, O. Habler, C. Hofstetter, R. Pusch, M. Müller, M. Welte and B. Zwissler (1998): Efficiacy of inhaled Prostanoids in Experimental Pulmonary Hypertension; Critical Care Medicine; 26(6): 1103-1109.
C. Hofstetter, M. Kleen, O. Habler, A.M. Allmeling, F. Krombach, B. Zwissler (1998): Recombinant Human Interleukin-10 Attenuates TNFa Production By Porcine Monocytes; European Journal of Medical Research; 3(6): 299-303.
S.Högl, C. Hofstetter, M. Flondor, E. Thein, B. Zwissler (2003): Efficacy and safety of a new jet nebulizer system for aerosolization in the ventilated rat. European Journal of Anaesthesiology, Vol. 20 (Suppl. 30) A259.
Kisch-Wedel H, Kemming G, Meisner F, Flondor M, Kuebler WM, Bruhn S, Koehler C, Zwissler B. The prostaglandins epoprostenol and Iloprost increase left ventricular contractility in vivo. Intensive Care Med 2003;29:1574-1583
Kuebler WM, Kisch-Wedel H, Kemming GI, Meisner F, Bruhn S, Koehler C, Flondor M, Messmer K, Zwissler B. Inhaled nitric oxide induces cerebrovascular effects in anesthetized pigs. Neurosci Lett 2003;348:85-88